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Quassia
The wood of several tropical American trees of the order Simarubeae, as Quassia amara, Picraena excelsa, and Simaruba amara. It is intensely bitter, and is used in medicine and sometimes as a substitute for hops in making beer.
A West Indian tree (Picraena excelsa) from the wood of which the bitter drug Jamaica quassia is obtained.
oewn 202368% interchangeable
Open English WordNet places these words in at least one shared synset. They share a lexicalised sense, but context, register and collocation should still be checked before substitution.